Source : Asian J Pharm Clin Res, Vol 7, Suppl 2, 2014, 177-181

Objective : To evaluate acute effects of IND9 supplementation on serum testosterone levels in healthy sedentary male subjects.

Methods : The study was designed as randomized, double blind, placebo controlled, two period, crossover study with 7 days of washout period using single study center. Sixteen healthy male subjects were randomized and received single dose of 600 mg (two capsules of 300 mg) of either IND9 or matching placebo capsules during each of the 2 study periods of 10 h each. Blood samples were collected three times at 3 h, 7 h and 10 h. The outcome measures were measurement of serum free testosterone (mFT) and total testosterone (TT), calculated levels of free testosterone (cFT), bioavailable testosterone (BT) levels and safety parameters.

Conclusion : Acute administration of IND9 capsule supplementation to sedentary males showed potential androgenic benefits with good safety profile.