Source : Nutrients 2024, 16(7)
Objective : Evaluate the effect of an orally administered ternary compound preparation on the status of physiological parameters of the ocular organ
Methods : A randomized, double-blind, cross-over study lasting with a “wash-out” period of 17 weeks evaluated a group of 23 people over the age of 50, who were subjects with presbyopia and burdened by prolonged work in front of screen monitors. The group of volunteers was recruited from people who perform white-collar jobs on a daily basis. The effects of the test substances contained in the preparation on visual acuity for distance and near, sense of contrast for distance and near, intraocular pressure, and conjunctival lubrication, tested by Schirmer test, LIPCOF index and TBUT test, and visual field test were evaluated.
Conclusion :
The results of the study showed that AKB used for 6 weeks did not change visual acuity during the first 6 weeks of treatment. It was not until the next cycle of the study that an improvement in near vision was observed in 92.3% of patients. This may indicate the potential of the formulation to correct near vision in patients with presbyopia.
On the other hand, an improvement in conjunctival hydration in the Schirmer test was observed in 80% of patients as early as week 6 of treatment. This effect decreased to 61.5% in the following weeks.